Founded in 1964 with only a handful of employees, the Kaiser Permanente Center for Health Research has since grown to nearly 250 employees in two states. The Center started in a small basement office in Portland, Oregon and fifty years later is housed a few miles away in a large, stand-alone building on Kaiser Permanente’s Interstate medical campus. This brief video features highlights from a half-century of conducting health care research and looks ahead to the Center’s future.