Department of Translational and Applied Genomics (TAG)

A clinician with samples in a lab

Our Research

Below is a list of projects that demonstrate how TAG is advancing knowledge of genomics and clinical application of genomic science.

CHARM: Cancer Health Assessments Reaching Many

  • CHARM team

Group Photo: Left front: Kate Mittendorf, Liz Shuster, Charisma Jenkins, Sandra Lee, Benjamin Wilfond, Katrina Goddard, Nangel Lindberg, Katie Porter, Gail Jarvik, and Robin Daily; Middle Right to left: Heather Feigelson, Frances Lynch, Mari Gilmore, Michael Leo, Tia Kauffman, Galen Joseph, Alan Rope, Jessica Ezzell Hunter, Laura Amendola, Meredith Vandermeer, and Katy Anderson; Back left to right: Carmit McMullen, John Dickerson, Beth Liles, and Michael Dorschner; CHR staff not pictured: Joanna Bulkley, Jake Allen, Ana Reyes, Jamilyn Zepp, Donna Eubanks, and Kristin Muessig

Collaborating Sites: Kaiser Permanente Northwest, Seattle Children’s Hospital, Denver Health, Columbia University, Dana-Farber Cancer Institute, Emory University, Kaiser Permanente Colorado, University of California at San Francisco, University of Washington

ClinGen: Clinical Genome Resource

  • clingen logo

CHR Study Team: Joanna Bulkley, Chris Catlin, Mari Gilmore, Charisma Jenkins, Ilya Ivlev, Stefan Massimino, and Christine Pak

Collaborating Sites: Full list is available here »

Connect for Cancer Prevention Study

  • connect logo

CHR Study Team: Mark Schmidt (site PI), Carmit McMullen (PI of participant advisory board), Charisma Jenkins, Dea Papajorgji-Taylor, Melanie Francisco, Chalinya Ingphakorn, Cheryl Johnson, Kristin Muessig, Sam Peterson, Yolanda Prado, Ana Reyes, and Sarah Vertrees

Collaborating Sites: National Cancer Institute, Division of Cancer Epidemiology and Genetics (NCI DCEG), Kaiser Permanente Colorado (KPCO), Kaiser Permanente Northwest (KPNW), Kaiser Permanente Hawaii (KPHI), Kaiser Permanente Georgia (KPGA), HealthPartners, Henry Ford Health System, Marshfield, Sanford Health, University of Chicago, NORC at the University of Chicago

Genetics of COVID-19 Susceptibility and Manifestations

CHR Study Team: Sheila Weinmann, Shawn Westaway, and Padma Dandamudi

Collaborating Sites: Kaiser Permanente NW (KPNW), National Human Genome Research Institute (NHGRI)

GRACE: Genetic Risk Analysis in ovarian CancEr

CHR Study Team: Sheila Weinmann, Jessica Hunter, Yolanda Prado, Jamilyn Zepp, and Ana Reyes

Collaborating Sites: Kaiser Permanente Northwest (KPNW), Kaiser Permanente Colorado (KPCO), Kaiser Permanente Washington (KPWA), Columbia University


Implementing Universal Lynch Syndrome Screening Across Multiple Healthcare Systems

CHR Study Team: Jessica Ezzell Hunter, Sara Gille, Jennifer Schneider, James Davis, and Alison Firemark

Collaborating Sites: Geisinger, Kaiser Permanente Northwest (KPNW), Kaiser Permanente Colorado (KPCO), Sutter Health, Meyers Primary Care Institute, HealthPartners, Harvard Pilgrim Healthcare, Catholic Health Initiatives

Kaiser Permanente Research Bank

  • CHARM team

Group Photo: Left to right: Lucy Fulton, Suzanne Gillespie, Alan Bauck, Padma Dandamudi, Joe Cerizo, Lindsay Jenkins, Chalinya Ingphakorn, Sheila Weinmann, Gwyn Saylor, and Kristina Booker; Not pictured: Beth Liles

Collaborating Sites: Kaiser Permanente Northwest (KPNW), Kaiser Permanente Colorado (KPCO), Kaiser Permanente Georgia (KPGA), Kaiser Permanente Hawaii (KPHI), Kaiser Permanente Mid-Atlantic (KPMA), Kaiser Permanente Northern California (KPNC), Kaiser Permanente Southern California (KPSC), Kaiser Permanente Washington (KPWA)

Prelude DCIS:

Multi-marker prognostic profile to predict invasive progression in DCIS patients

CHR Study Team: Sheila Weinmann, Michael Leo; Previous team members: Melanie Francisco, Kristina Booker, and Charisma Jenkins

Collaborating Sites: Kaiser Permanente Northwest (KPNW), Prelude Corporation

Surveillance for Outcomes of Genomic Medicine Policies‚Äč

CHR Study Team: Jessica Ezzell Hunter, Kristin Muessig, and Lindsay Jenkins

Collaborating Sites: Kaiser Permanente Northwest (KPNW), Harvard Pilgrim Healthcare, Kaiser Permanente Hawaii (KPHI), Kaiser Permanente Colorado (KPCO), Geisinger, Henry Ford Health System

TMEM: Tumor MicroEnvironment of Metastasis 

KPNW Study Team: Sheila Weinmann, Judy Donald, Melanie Francisco, Sarah Vertrees, Jenny Liu, Tami Roland, and Lina Issak

Collaborating Sites: Kaiser Permanente Northwest (KPNW), Albert Einstein College of Medicine

Biospecimens Resources 

In alignment with CHR’s commitment to make specimen resources available for collaborative scientific research, CHR maintains biorepositories containing samples from KPNW members that can be linked to their electronic medical records (EMR). This includes blood derived samples (e.g., DNA) stored at CHR’s Northwest Research Laboratory, archived surgical cancer specimens stored at our Northwest Tissue Library, and genomic data generated by prior studies at CHR.   

Learn more on our Biospecimens Resources page »

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