ProjectsCafe

Cancer Treatment: Costs and Impact on Care

Café

To date, there have been no prospective studies evaluating the impact of the interventions aimed at reducing financial hardship among people with cancer.

Up to half of people with cancer experience financial hardship. Cancer-related financial hardship is associated with several adverse intermediate and health outcomes, including poor quality of life, treatment non-adherence, and lower survival.

An increasing body of observational evidence suggests that communication about financial concerns and out-of-pocket (OOP) costs early in the treatment trajectory and in partnership with the care team could help to prevent or lessen financial hardship. This type of communication could be delivered through patient navigation programs and is consistent with both patient and care team preferences.

However, to date there is no evidence from randomized trials suggesting that navigation during the active treatment period reduces financial hardship. Further, no intervention-based studies have provided evidence on the most effective ways to mitigate cancer-related financial hardship. CAFÉ (Cancer Financial Experience) is a randomized controlled trial to test the effectiveness of the financial navigation program in reducing financial hardship.

CAFÉ participants randomized to the intervention group will receive a written list of financial assistance resources plus 6 months of personalized outreach and assistance with financial concerns. Participants randomized to the control group (enhanced usual care) will receive the same written list of financial assistance resources that the intervention group participants receive.

The intervention is based on the research team’s prior studies and is informed by a conceptual framework of how patient-centered communication can improve health.

We have designed the intervention in close partnership with KPWA and KPNW members, clinic teams, administrative staff, and health plan leaders. The CAFÉ study has the full support and partnership of clinical and operational teams at KPWA and KPNW.

Specific aims and hypotheses:

Aim 1: Compare self-reported financial distress between patients receiving the CAFÉ intervention versus a control group at 12-month follow up.

  • Hypothesis: Participants randomized to the intervention group will report lower levels of financial distress compared to those in the control group at 12-month follow-up.

Aim 1a: Compare self-reported health-related quality of life between patients receiving the CAFÉ intervention versus a control group at 12-month follow up.

  • Hypothesis: Participants randomized to the intervention group will report higher self-reported health-related quality of life compared to those in the control group at 12-month

Aim 2: Compare health service use between patients receiving the CAFÉ intervention versus a control group at 12-month follow up.

  • Hypothesis: Fewer participants randomized to the intervention group will forgo care and experience delays in care com pared to those in the control group at 12-month follow-up.

Aim 3 (exploratory): Assess patient-level factors influencing variability in dose of the CAFÉ intervention.

Project Team

Investigators:

  • Amanda Petrik, Kaiser Permanente Center for Health Research (Site Investigator)
  • Nora Henrikson, KP Washington Health Research Institute (Principal Investigator)
  • Mateo Banegas, University of California San Diego (Principal Investigator)

Biostatisticians (Co-Is):

  • John Dickerson, Kaiser Permanente Center for Health Research
  • Melissa Anderson, KP Washington Health Research Institute

Project Managers:

  • Daniel Sapp, KP Center for Health Research
  • Aaron Scroll, KP Washington Health Research Institute

Research Associates:

  • Jennifer Schneider, KP Northwest Center for Health Research

Interventionists:

  • Blake Locher, Jen Rivelli, KP Northwest Center for Health Research
  • Deborah King, KP Washington Health Research Institute

REDCAP Designer:

  • Robin Garcia, KP Washington Health Research Institute

Analysts:

  • Arvind Ramaprasan, KP Washington Health Research Institute
  • Erin Keast, KP Northwest Center for Health Research

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